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(More customer reviews)I am a layman. I have provided Vitamin D3 at this dosage to a number of individuals with auto-immune diseases such as type II diabetes, high blood pressure, rheumatoid arthritis and congestive obstructive pulmonary disease. In almost every case, these individuals have experienced a reduction of symptoms. There is a very extensive literature supporting the theory that Vitamin D reduces auto-immune symptoms. Most human cells have a Vitamin D (VDR) receptor and these cells do not mature unless Vitamin D is available. This in itself may explain why Vitamin D3 provides such a wide range of health benefits.
It is also important to assure that you get minimums of calcium (1000 mg), magnesium (500mg) and zinc (15mg) from diet or supplements as Vitamin D "uploads" these minerals from the diet. Many manufacturers provide an inexpensive three (large!) pill daily cal-mag-zinc supplement based on these minimums. You can find these formulations at Walmart and large chain drugstores. They will also carry liquid formulas providing calcium and magnesium.
Vitamin D regulates gene expression, appears to be essential for proper immune system function, fights infection including bacterial infections such as bacterial colds, tuberculosis and bacterial pneumonia, reduces the incidence of cancer, and strengthens bone and muscle. Carlson informs me that the Vitamin D3 this product is made from lanolin (sheep wool fat) irradiated with Ultraviolet B light. As a vegetarian, I appreciate the fact that life is not taken to produce this product.
Spring, fall and summer noontime sunshine exposure provides adequate Vitamin D. Stay out a short time if your skin is light, but stay out longer if your skin is dark. Very light-skinned individuals can make adequate Vitamin D from arm and face noontime exposure in 15 minutes or less. Very dark-skinned individuals may require up to 2 hours to achieve the same level. Skin color is adaptive to sunlight levels, so that people from equatorial regions are darker-skinned and people from Iceland, who are starved for sun and Vitamin D, are very light-skinned. Get it? That's all there is to skin color. It's interesting that primitive cultures living far from the equator prize the few foods that naturally concentrate Vitamin D3, like fish liver oil and sea mammal blubber. Cod liver oil is about the only food supplement that provides a lot of Vitamin D. Milk has a little added and you can get 2000 a day by drinking 20 8-ounce glasses!
It is important that individuals who are not frequently exposed to the sun, who regularly wear sunblock or who are dark-skinned take Vitamin D3 supplements. Also, individuals who are elderly or obese generally require more Vitamin D3. Many researchers feel these groups should take 5,000 i.u. daily. As you get older you have more difficulty absorbing D and fat cells tend to sequester (trap) Vitamin D. If you are too poor to get tested for Vitamin D deficiency but are not frequently exposed to direct sunlight on your skin, I would encourage you to take 2000 i.u. daily of Vitamin D3. The FDA says a daily dose of 2,000 i.u. is completely safe. Other competent researchers feel a dose of 10,000 i.u. is generally safe, and very beneficial in some conditions such as multiple sclerosis. If your physician has not read recent literature about Vitamin D, encourage a thorough review of widely-available research findings on D. One source is [...], Dr. John Cannell's site. You can do your own research. There are many research articles and abstracts available on the Net. Search for "Vitamin D" deficiency to get started.
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