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(More customer reviews)Unless one has a specific condition that is being treated with the product, it is not really possible to give a subjective review. Therefore, I am giving the facts on the product so you can evaluate its worth. Of course L-Carnitine is one of the big five to prevent heart attacks, along with D-Ribose, Magnesium, COQ10, and Glutamine. There are other substances that are also extremely important. I take all of these products and have moved up to the Life Extension to enhance the performance. Actually I was severely fatigued from over work and for two years was at risk for a heart attack. I had constriction in the chest area, and constriction pain like a tournequet on my arm as well. I slept a lot and took these products and now I am Queen Kong. It took continunous sleep of 12 hours a day and more for over a year and the rest of the time I could just lay still and listen to faith teaching and watch DVDs. Then for the rest of the two years I slept 12 hours and could get up for awhile and after I began taking the products the heart pain was totally gone and I can do lots of activity without fast heart palpitation. One thing to remember is that when you first start feeling well you think you are recovered, but you can easily have a set back, I learned not to overdo the activity at first or I would be flat out in bed for two weeks. I just want to go back to walking five miles a day, etc, but I had to build myself back up. I have noticed a distinctive change in my heart from taking these products from Life Extension over the extensive rest and sleep. Now the biggy, getting the fat off that accumulated from not being active. However, that will take care of itself now that I am active, as I eat right.
Now to the important scientific facts on the product. The amino acid acetyl-L-carnitine boosts mitochondrial energy production through its ability to facilitate fatty acid transport and oxidation in the cell.
A major cause of aging is reduction in the energy-producing components of the cell, resulting in reduced cellular metabolic activity and the accumulation of cellular debris.1-7 L-carnitine helps maintain cellular energy metabolism by assisting in the transport of fat through the cell membrane and into the mitochondria within the cell, where fats are oxidized to produce the cellular energy ATP.8-13
Acetyl-L-carnitine is the acetylated ester of the amino acid L-carnitine. Acetyl-L-carnitine is an endogenous mitochondrial membrane compound that helps maintain mitochondrial bioenergetics and lowers the increased oxidative stress associated with aging. Acetyl-L-carnitine and L-carnitine are absorbed into the bloodstream efficiently. Both are effective at carrying fatty acids across the membrane into the cell where they are burned as energy and utilized efficiently by the mitochondria. Acetyl-L-carnitine also guards against oxidative damage.Amyloid-beta peptide is a principal component of senile plaques and is thought to be a contributor to the aging process. Acetyl-L-carnitine exerts protective effects against oxidative stress.
With the discovery of acetyl-L-carnitine arginate the benefits of acetyl-L-carnitine can now be greatly augmented. Acetyl-L-Carnitine Arginate is a patented form of carnitine that stimulates the growth of neurites in the brain. Studies show that acetyl-l-carnitine-arginate stimulates the growth of new neurites by an astounding 19.5% (as much as Nerve Growth Factor itself). Acetyl-l-carnitine-arginate acts together with acetyl-l-carnitine to increase neurite outgrowth.
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